RNS Number:9430R
Isotron PLC
11 November 2003



                           SCHEDULE 10
 
             NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   NAME OF COMPANY

     ISOTRON PLC

2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

      STANDARD LIFE INVESTMENTS

3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18

      2 ABOVE

4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.

      STANLIFE NOMINEES LIMITED

5)   Number of shares/amount of stock acquired.

      344,482

6)   Percentage of issued Class
      1.63%

7)   Number of shares/amount of stock disposed
       

8)   Percentage of issued Class


9)   Class of security

      25P ORDINARY SHARES

10)  Date of transaction

      10/11/03

11)  Date company informed

       11/11/03

12)  Total holding following this notification

      1,208,370
               
13)  Total percentage holding of issued class following this notification

       5.73%

14)  Any additional information



15)  Name of contact and telephone number for queries

       MRS C E BRAY
       01793 567900

16)  Name and signature of authorised company official responsible for 
     making this notification

     Date of Notification ...11 NOVEMBER 2003.......



                      This information is provided by RNS
            The company news service from the London Stock Exchange

END

HOLNKDKQPBDDKDD